Hang oversize pictures?

Go to Home Depot, the fastener aisle, look for zip its, they are over sized screws with a hole in the middle for another screw to go into, which expands the first screw into the drywall, some people call them drywall anchors. Buy the ones made of zinc, not the plastic ones, they are rated by how many pounds that they will hold. This works very well if you cannot find a stud where you are trying to hang the picture.